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90 Veg Capsules

Supports stress hormones, nervous system & HPA Axis function.*


  • Gluten Free
  • BPA-Free
SKU: 131020

Ingredients + Recommended Use

  • Serving Size: 2 Capsules
  • Servings Per Container: 45

Active Ingredients

  • Manganese (as manganese citrate), 10 mg
  • Ashwagandha (root) extract (Withania somnifera), 500 mg
  • N-acetyl-L-tyrosine, 500 mg
  • Pituitary (anterior) Tissue lyophilized (bovine), 200 mg
  • Rhodiola rosea (root)extract, 100 mg
  • Adrenal tissue lyophilized (bovine), 40 mg
  • Hypothalamus tissue lyophilized (porcine), 40 mg

Other Ingredients

Hypromellose (capsule), vegetable stearte, silica

Usage Direction

2 Capsules daily or as direct by a health care practitioner.


*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Aperture Energetics and Physica Energetics are not medical facilities, nor do we provide any medical advice on
any of the products. Our supplements are intended to be used under the close
supervision and direct care of a licensed or certified healing arts professional.
Products are only sold through licensed or certified healing arts
practitioners. Aperture Energetics and Physica Energetics offer this
information with the expectation that practitioners shall use their own
discretion, perform their own research, and rely on their own clinical
experience and practice according to their scope of practice and the limits of
their license or certification.

Product Overview

HPA Axis LF has been designed to nutritionally support the specific pathways and components, which are a significant Causal Chain Adaptogenic Cascade Design in and of themselves.*

The hypothalamic, pituitary, adrenal (HPA) axis is the central stress response system. The HPA axis has been accurately described as a dynamic inter-weaving dance between the central nervous and endocrine systems. In fact, you may also refer to it as the ultimate hormonal adaptogenic cascade.

As such, the HPA axis is responsible for the central adaptation component of the stress response, regulated by a complex system of negative feedback loop mechanisms.

With repeated exposure to stressors, including pathogens, physical and emotional trauma, and environmental triggers, the body, mind, and heart may begin to entrain with these stressors, creating repeated and sustained HPA axis activation.

Emotionally charged events or trauma early or even later in life may significantly impact the coordination of the HPA axis and the patterns of the body’s stress reaction and response.

Under conditions of normal exposure to cortisol, tissues only experience glimpses of alarm catecholamines and cortisol. However, with repeated exposure to stress, the sensitized HPA axis may continue to hyper-secrete cortico-releasing hormone (CRH) from the hypothalamus. Over time, CRH receptors in the anterior pituitary will become down-regulated and can produce depression and anxiety symptoms.

It is vital to support healthy cortisol levels to ensure the hypothalamus and pituitary glands maintain the appropriate level of sensitivity to the negative feedback of cortisol.

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